One full week of the college football season has been completed, and we're about to learn a lot more. The Week 2 schedule is packed, featuring four games between ranked teams, on home fields rather than at neutral sites: No. 5 Oklahoma at No. 2 Ohio State, No. 13 Auburn at No. 3 Clemson, No. 15 Georgia at No. 24 Notre Dame and No. 14 Stanford at No. 6 USC.
What should you watch this week? Let's run through all of the weekend's key games.
All times are Eastern, and within each time slot games are previewed in order of importance and watchability.
Note: Hurricane Irma has caused several schedule changes, including the cancellation of No. 16 Miami at Arkansas State, Louisiana Monroe at No. 10 Florida State, Northern Colorado at No. 22 Florida, No. 21 South Florida at Connecticut and Memphis at UCF.
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No. 11 Oklahoma State at South Alabama
8 p.m., ESPN2
The Cowboys surely won't be taking South Alabama lightly, given the Jaguars' recent success in nonconference play. Last year, South Alabama won at Mississippi State, 21-20, and it swept a home-and-home with Mountain West champion San Diego State the past two seasons. Then again, the Jaguars lost 47-27 to Ole Miss last week, giving up 429 passing yards. Their defense will face another difficult opponent in the Cowboys' high-powered offense, which opened the season by routing Tulsa 59-24 with a highly efficient and explosive day from QB Mason Rudolph and his talented receiving corps. A strange road trip like this on a Friday night may look like a trap, but this Oklahoma State offense is too dangerous to fall here.
Pick: Oklahoma State 52, South Alabama 21
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Saturday Early Afternoon
No. 17 Louisville at North Carolina
Louisville made too many mistakes and struggled to beat Purdue in its opener, but Week 1 went far better for the Cardinals than the Tar Heels, who lost at home to California. Lamar Jackson was his typical self, throwing for 378 yards and rushing for 107 yards. North Carolina, which lost No. 2 pick Mitch Trubisky at quarterback, averaged five yards per pass attempt in splitting time between Chazz Surratt and LSU transfer Brandon Harris. The Cardinals have a better defense than Cal, and they also have a far better offensive weapon in Jackson. Despite last week's frustration against Purdue and the lingering issues on the offensive line, Louisville has the clear advantage.
Pick: Louisville 35, North Carolina 21
Iowa at Iowa State
The rivalry series had been competitive in recent years, but Matt Campbell's debut as Iowa State's coach didn't start well with a 42-3 loss at Kinnick Stadium last season. Given the Hawkeyes' passing game questions, expect this to get back to being a close game. The Iowa defense was impressive in overwhelming Josh Allen and Wyoming last week, but the offense ran only 56 plays for 263 yards. Iowa will surely use a heavy dose of the backfield combination of Akrum Wadley and James Butler, and it can again ride its defense to a win -- although standout Cyclones wideout Allen Lazard will test a new-look Hawkeyes secondary.
Pick: Iowa 23, Iowa State 17
Florida Atlantic at No. 9 Wisconsin
Noon, Big Ten Network
Lane Kiffin's Florida Atlantic debut was a rain-delayed marathon that lasted into the early hours of last Saturday morning. The delays couldn't stop the inevitable: a 42-19 loss to Navy in which the Owls allowed 416 rushing yards. While that was going on, Wisconsin rebounded from a slow start to crush Utah State by 49. The Badgers are too physical, too stout defensively and likely too effective in the running game for Kiffin's Owls to keep up at Camp Randall Stadium.
Pick: Wisconsin 41, Florida Atlantic 16
Cincinnati at No. 8 Michigan
The last time Luke Fickell saw Michigan as a head coach, the Wolverines beat Ohio State for the only time since 2003. That was 2011, as the interim head coach in Columbus. Now, Fickell is in his first season as head coach at Cincinnati, and he has to go into Ann Arbor and meet a young but still talented and still potentially dominant defensive Michigan team. The Bearcats' opener against Austin Peay -- an FCS team that went 1-45 the past four years -- was uninspiring, as they were out-gained 313 to 248 and won by 12. Michigan still has issues to work out on offense, but its defensive front will control this game.
Pick: Michigan 35, Cincinnati 13
Northwestern at Duke
This is the third year in a row the Wildcats and Blue Devils will meet. Northwestern won each of the past two seasons, including a 24-13 victory in Evanston last September. Duke gets Northwestern at home this time with a more experienced quarterback than a year ago, as Daniel Jones was playing only his third game as a freshman in that loss. Now, he's a potential rising star under coach David Cutcliffe, hoping to out-duel Northwestern's Clayton Thorson, who was sharp in last week's 31-20 win over Nevada -- one in which the Wildcats struggled for much of the game before he came through late. Despite last week's problems, the edge goes to Northwestern's superior defense.
Pick: Northwestern 27, Duke 23
Other ranked teams in action: Charlotte at No. 19 Kansas State (Noon)
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Saturday Late Afternoon
Pittsburgh at No. 4 Penn State
3:30 p.m., ABC
The rivalry resumed after a decade-and-a-half hiatus last season, with Pitt storming out to a three-TD lead in the first half, Penn State storming back to give itself a chance for the comeback win and Pitt shutting the door with a late interception. Penn State put up big passing numbers in that game despite the game-ending interception by Trace McSorley, who has since developed into a master of the long ball in a big-play Nittany Lions offense that features an improved line, an athletic receiving corps and the nation's best tailback in Saquon Barkley. The Penn State-Pitt result likely would have been much different in November than September last year, and it's subsequently likely to be much different this September, with much of the roster from a Penn State breakthrough season returning.
The Panthers still have questions in pass defense, where they were repeatedly burned last year, and it doesn't help that top defensive back Jordan Whitehead is suspended. They also have questions to answer on offense after a sluggish effort against Youngstown State that required overtime. The Panthers still have a couple big-play threats in Quadree Henderson and Jester Weah, but they have a new coordinator, Shawn Watson, and a new QB in USC transfer Max Browne. Circumstances in this rivalry have changed a lot in the past year, and in its first trip to Happy Valley since 1999, Pitt's going to have a difficult time keeping pace with this explosive Nittany Lions squad.
Pick: Penn State 44, Pittsburgh 20
Nebraska at Oregon
4:30 p.m., Fox
The Ducks are favored by nearly two touchdowns despite the fact that they went 4-8 last year, lost at Nebraska by three and have played only one game against an FCS team so far under new coach Willie Taggart. That's a lot of points for a team with so much to prove, particularly on defense. It's not as if the Ducks are alone in needing improvement on defense, however. Nebraska opened its season by beating Arkansas State 43-36, allowing 415 passing yards (albeit on 68 attempts) and 32 first downs. The Ducks are better on the offensive line this year and should have an excellent running game; their biggest issue on offense is developing receivers for promising sophomore QB Tanner Lee.
This is capable of being an explosive Oregon attack, and it has more proven weapons than Nebraska does around transfer quarterback Tanner Lee. There's little doubt that Nebraska will be able to run the ball the Ducks' work-in-progress defense, but after an easy start against Southern Utah, the Taggart era can really get a jolt of confidence here, led by tailback Royce Freeman.
Pick: Oregon 45, Nebraska 30
No. 23 TCU at Arkansas
3:30 p.m., CBS
It's hard to imagine this coming close to topping the wild Arkansas win over TCU in Fort Worth last September. Arkansas won 41-38 in double OT after blowing a lead in the fourth quarter, coming back to tie and then blocking a field goal at the end of regulation. For how much that game was, both teams ended up having disappointing seasons, as TCU slipped to 6-7 and Arkansas went 7-6. After both teams easily handled FCS opponents in Week 1, we'll get a much better gauge of progress from both in Fayetteville on Saturday.
TCU is one of the nation's most experienced teams, and it's trying to get more consistent from quarterback Kenny Hill, who's surrounded by a solid group of playmakers. They'll attack an Arkansas defense that was often horrendous last year, ranking 123rd in yards per play allowed. Former Iowa State head coach Paul Rhoads is now Arkansas' defensive coordinator, and he's charged with, first and foremost, shoring up the run defense. Arkansas is at home, but this is capable of being a more reliable, well-rounded TCU team, one that has fewer holes than the Razorbacks.
Pick: TCU 31, Arkansas 27
Hawaii at UCLA
5 p.m., Pac-12 Network
It still seems impossible that we're talking about a 1-0 UCLA. Last Sunday, the Bruins trailed 44-10 late in the third quarter against Texas A&M. QB Josh Rosen, after missing the second half of last season with a shoulder injury, threw for 292 yards in the fourth quarter to lead the Bruins to the second-biggest comeback in college football history. So… how does UCLA follow that one? Fortunately, the dangerous road trip to Memphis isn't until next week. With a short week, the Bruins stay home and play a solid but beatable Hawaii. Standout Warriors LB Jahlani Tavai can cause some havoc against this UCLA offensive line, but Hawaii is still going to have a difficult time slowing down a now-healthy Rosen.
Pick: UCLA 35, Hawaii 17
Western Michigan at Michigan State
3:30 p.m., Big Ten Network
Just because coach P.J. Fleck, WR Corey Davis and QB Zach Terrell are gone doesn't mean Western Michigan still can't be dangerous, especially against a vulnerable Michigan State:
In the last 3 years, Michigan St is 1-11 ATS and has lost 8 of 12 games outright as a favorite of 10 or fewer points. Underdog WMU howling?- Chris Fallica (@chrisfallica) September 7, 2017
The Spartans, who went 3-9 last year, opened with a 35-10 win over Bowling Green, but the Broncos are a much tougher MAC opponent than the Falcons, as they showed at USC last week. Western Michigan hung with USC most of the game before losing 49-31 thanks to a couple late Trojans scores. The Broncos are solid on the offensive line and have an have a deep group of running backs. Expect Western Michigan to at least keep this one close against a largely unproven Michigan State that's a long way away from the playoff team we saw two years ago.
Pick: Michigan State 27, Western Michigan 23
Fresno State at No. 1 Alabama
3:30 p.m., ESPN2
After beating Incarnate Word, an FCS team, 66-0 in Jeff Tedford's coaching debut, Fresno State has already matched last year's win total. With an experienced offense and an experienced new offensive coach, Fresno State will be improved from last year, but not nearly enough to stay anywhere close to Alabama. Perhaps Alabama will have a slight letdown after the emotional high of the opening win over Florida State, but the Crimson Tide will physically dominate the Bulldogs and cruise.
Pick: Alabama 42, Fresno State 10
San Jose State at Texas
3:30 p.m., Longhorn Network
The initial optimism for instant Texas success under Tom Herman slipped away when the Longhorns were gashed by Maryland for 51 points in a home loss in Week 1. In the aftermath of a mistake-filled game, Herman said that he couldn't just "sprinkle some fairy dust" on the team to immediately fix all its problems. Herman's former employer, Ohio State head coach Urban Meyer, took exception to such a statement, telling CBS Sports, "It's like a new generation of excuse," and criticizing coaches who blame players they inherited for a lack of success.
Nothing can seem to go smoothly in Austin anymore, and the status of QB Shane Buechele is up in the air because of a bruised throwing shoulder. By no means is a Texas win ever guaranteed at this point, but the Longhorns should be able to take it relatively easy against San Jose State (which lost to former Texas coach Charlie Strong and SF 42-22 after blowing an early lead on Aug. 26) and regain some confidence before going on the road to USC next week.
Pick: Texas 41, San Jose State 17
Other ranked teams in action: Delaware at No. 18 Virginia Tech (3:30 p.m., ACC Network); Indiana State at No. 25 Tennessee (4 p.m., SEC Network)
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Saturday Prime Time
No. 5 Oklahoma at No. 2 Ohio State
7:30 p.m., ABC
Ohio State 45, Oklahoma 24 was one of the most disappointing games of the 2016 college football season. It's a great home-and-home series -- their only other two meetings were in 1977, an all-time classic, and 1983 -- but early last season, the result was a letdown: The Buckeyes controlled the game, leading 35-17 at halftime and never looking back. In some ways, it's easy to see something similar happening: Oklahoma lost a Hall of Fame-bound coach, a Heisman finalist receiver and two NFL running backs. Ohio State, meanwhile, is far more experienced than it was a year ago, and it gets to host the Sooners at the Horseshoe.
This is Lincoln Riley's first big game as head coach, but don't expect a similar Ohio State rout. Oklahoma has the passing edge with Baker Mayfield over Ohio State's J.T. Barrett -- who still struggled to stretch the field in the opener at Indiana -- and it has arguably the nation's best offensive line, which can lessen the impact of the Buckeyes' absurdly talented defensive line. The Sooners are breaking in new passing targets beyond TE Mark Andrews, but Mayfield can still attack a new-look secondary after Indiana picked on it last week. Will it be enough to win? That's another matter. Ohio State is deeper and more physical. It found a new go-to weapon in true freshman running back J.K. Dobbins, it's going to be better on the offensive line than it was last year and it will be difficult to run on.
There are lingering concerns about the Ohio State offense, but the Buckeyes are again the more complete team.
Pick: Ohio State 36, Oklahoma 31
No. 13 Auburn at No. 3 Clemson
7 p.m., ESPN
Clemson had enough close calls last year that its opener at Auburn was sort of forgotten. Facing an uncertain Auburn passing game, Clemson barely escaped with a 19-13 win in which the teams combined to commit five turnovers. Since then, Clemson has claimed a national championship and lost Deshaun Watson, and Auburn has brought in Baylor transfer Jarrett Stidham as its new quarterback. Both Tigers teams blew out inferior opponents last week, with new Clemson QB Kelly Bryant looking a bit sharper against Kent State than Stidham did against Georgia Southern. That was only Week 1, though. The real tests start Saturday in Death Valley, where two high-profile new QBs will meet talented defensive fronts.
The biggest strength in this game is the vaunted Clemson defensive line, which features Clelin Ferrell, Dexter Lawrence, Christian Wilkins and Austin Bryant, plus depth behind them. Clemson is strong in both trenches, in fact, making the transition to the post-Watson era easier. The defensive line will be charged with pressuring Stidham and slowing down a run game that is dealing with an injury to Kerryon Johnson but gets starter Kamryn Pettway back from a one-game suspension. Bryant seamlessly fit into Clemson's offense last week, and while Auburn's defense is a massive step up from Kent State's, he does benefit from playing this game at home and having more proven receivers thanks to the return of Deon Cain, Hunter Renfrow and Ray-Ray McCloud.
Pick: Clemson 24, Auburn 20
No. 15 Georgia at No. 24 Notre Dame
7:30 p.m., NBC
The Bulldogs and Fighting Irish have met only one time ever, and the result was Georgia claiming its first and only national championship in 1980 in the Sugar Bowl despite completing only one pass all game. The stakes aren't nearly as high this time, but there's substantial pressure on both sides heading into this highly anticipated game in South Bend.
Notre Dame coach Brian Kelly is trying to bounce back and get back into the good graces of the Fighting Irish faithful after last year's 4-8 record. He has a promising new quarterback, Brandon Wimbush, and a new-look coaching staff. In a Week 1 rout of Temple, Wimbush was aided by a dominant running game behind one of the nation's best offensive lines. Against a talented and experienced Georgia defense, that line will be crucial on Saturday.
Georgia coach Kirby Smart is trying to put the Bulldogs on an upward trajectory after an uninspiring 8-5 first season. He has veteran running backs in Nick Chubb and Sony Michel to go along with that talented defense, but he'll unexpectedly be playing a new quarterback, Jake Fromm. The freshman drew rave reviews in the offseason, and he'll make his first career start in a hostile environment because of the sprained knee of starter Jacob Eason. New Notre Dame coordinator Mike Elko is trying to rebuild this defense and generate more pressure, and they'll try to do so against a new QB playing behind what was an underwhelming offensive line last year.
Both quarterbacks are wild cards, but with better offensive line and receiving corps on his home field, Wimbush is in better position to propel his team to a win on Saturday night.
Pick: Notre Dame 28, Georgia 27
No. 14 Stanford at No. 6 USC
8:30 p.m., Fox
It's the 10-year anniversary of Stanford beating USC in one of the biggest upsets in college football history. Things, of course, have changed drastically since then: Stanford has been the stronger program since Pete Carroll left USC and has won seven of the past nine games in the series. The tables are expected to turn a bit again: While Stanford is still strong -- it has finished in the AP top 12 in six of seven seasons -- USC is back on the rise, a preseason top-five team with a prized young quarterback in Sam Darnold and more depth than its had in a while. With USC and Washington reinvigorated, Stanford suddenly became almost an afterthought in preseason debates about the conference title, a clear third choice entering the year.
Despite USC's trouble against Western Michigan last week, it comes in with the much more proven quarterback in Darnold. The question is how the defense will hold up against Stanford's offensive line and running game, now led by Bryce Love. The Cardinal crushed Rice in Australia two weeks ago and have had a couple weeks to prepare for USC. Stopping USC isn't just about slowing down Darnold, though. It's also about slowing down rising star tailback Ronald Jones II, who stole the show on offense against Western Michigan with 159 yards and three TDs on the ground.
USC has high hopes of contending for a national championship, but first it needs to start beating Stanford again.
Pick: USC 31, Stanford 27
South Carolina at Missouri
7 p.m., ESPN2
Both teams had somewhat strange Week 1 wins, South Carolina's much bigger than Missouri's. The Gamecocks beat N.C. State by a touchdown with the help of a kick return touchdown and two fumble recoveries, in a game in which they ran only 50 offensive plays for 246 yards. Missouri played Missouri State, an FCS team, and won 72-43 after giving up 35 first-half points. Mizzou has significant questions on defense, and while QB Drew Lock put up huge numbers last week, he hasn't played nearly as well against Power Five opponents. Lock has the bigger numbers, but South Carolina has the better quarterback in sophomore Jake Bentley.
Pick: South Carolina 35, Missouri 34
Other ranked teams in action: Chattanooga at No. 12 LSU (7:30 p.m., SEC Network); Montana at No. 7 Washington (8 p.m., Pac-12 Network)
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Saturday Late Night
Boise State at No. 20 Washington State
10:30 p.m., ESPN
It's a big game week in Pullman, where a ranked Cougars squad gets set to host annual Group of Five power Boise State … and Mike Leach is talking about Bigfoot and aliens:
On the field, the Cougars started their season with a 31-0 win over Montana State, a result not to be taken for granted, given that each of the past two otherwise successful seasons began with a loss to an FCS team. This week, Wazzu meets a Boise State squad it lost to last year, 31-28 on the blue turf. The Broncos survived against Troy last week, with an uneven performance from all-conference QB Brett Rypien and some playing time for Kansas transfer Montell Cozart.
While the Boise State defense played well against Troy, a unit that had a lot of attrition from last year will be severely tested by veteran QB Luke Falk and Washington State's prolific Air Raid attack.
Pick: Washington State 38, Boise State 30
Utah at BYU
10:15 p.m., ESPN2
The Holy War is an underappreciated rivalry nationally. Locally, it's among the fiercest and most physical in the sport. Utah has actually won six in a row in the series, with five of those six wins decided by a touchdown or less. This year, both face questions on offense. Utah installed has a new pass-heavy scheme under new coordinator Troy Taylor with a new quarterback in Tyler Huntley. Huntley threw for 227 yards in an opening 37-16 win over North Dakota. BYU has played twice, a lackluster 20-6 win over Portland State followed by an ugly 27-0 shutout at the hands of LSU in which it ran 38 plays for 97 yards -- the antithesis of offensive coordinator Ty Detmer's playing days under LaVell Edwards. Utah's status on offense is more an open-ended question; BYU faces significant problems. Thus, while this game is in Provo, the Utes get the slight edge.
Pick: Utah 19, BYU 17
Houston at Arizona
10:30 p.m., ESPNU
The Cougars will make their 2017 debut under new coach Major Applewhite after their opener at UTSA was canceled because of Hurricane Harvey. Applewhite has yet to name a starting quarterback, but the favorite has been Texas A&M transfer Kyle Allen, a former five-star recruit who had starting experience with the Aggies. The Cougars won Power Five games against Louisville (twice), Oklahoma and Florida State the past two years, and they have another talented roster headlined by standout DT Ed Oliver. With an improved running game and a better defensive front than Arizona's, the Cougars have a good chance to go into Tucson and earn another win over a power conference opponent.
Pick: Houston 38, Arizona 31
Minnesota at Oregon State
10 p.m., FS1
After a passable 17-7 win over Buffalo to start the P.J. Fleck era, Minnesota will get its first Power Five test on the road in Corvallis against an Oregon State team it beat 30-23 to open 2016. The Beavers, in their third season under Gary Andersen, haven't gotten off to the start they'd hope for, as they were blown out 58-27 in their opener against Colorado State (which scored three points against Colorado six days later), then barely edged FCS team Portland State 35-32 last week. Neither team is easy to get a read on early this season, but with a stronger defense, we'll go with the Golden Gophers to escape with a tight win on the road.
Pick: Minnesota 26, Oregon State 24
San Diego State at Arizona State
11 p.m., Pac-12 Network
The Aztecs beat California from the Pac-12 in an 11-win season last year, and this year they face two Pac-12 opponents in a row: at Arizona State this week, vs. Stanford next week. The run-heavy nature of the San Diego State offense will make life easier on the vulnerable Arizona State defense, which was especially burned in the passing game last year. Still, it's not as if the Sun Devils are stout against the run, either, and the Aztecs have a talented senior in Rashaad Penny stepping up to replace the prolific Donnel Pumphrey.
Pick: San Diego State 34, Arizona State 31